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ChemInform Abstract: Mukaiyama-Michael Reaction of Cyclic Ketene Silyl Acetals and Enones. Importance of Ring Flexibility in Electron Transfer Process.

โœ Scribed by Y. FUJITA; S. FUKUZUMI; J. OTERA


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
28
Category
Article
ISSN
0931-7597

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Mukaiyama-Michael reaction of cyclic ket
โœ Yukihiro Fujita; Shunichi Fukuzumi; Junzo Otera ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 164 KB

Michael reaction of macrocyclic ketene silyl acetals or a-enones occurs smoothly under electron transfer conditions while the reaction of 6-membored analogs is more sluggish, indicating the importance of the ring flexibility to allow the a,~-carbon-carbon bonds of both reaction components to rotate