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Diastereoselective Darzens Condensations.

โœ Scribed by Thierry J. R. Achard; Yuri N. Belokon; Jamie Hunt; Michael North; Francesca Pizzato


Publisher
John Wiley and Sons
Year
2007
Weight
33 KB
Volume
38
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES


Aldol condensations of chiral ฮฑ-haloimid
โœ Ahmed Abdel-Magid; Ivan Lantos; Lendon N. Pridgen ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 214 KB

Sumunary: --\_-Enantiomerically pure benzyl cis-a,B-epoxycarboxylates were prepared by a modified Darsens procedure utilizing aldx condensation reactions of chiral a-haloimidates with various aldehydes. A unique chirality reversal was observed using Zincenolates.

Diastereoselective aldol condensations o
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The reaction of tin enolates of cyclohexanone or propiophenone with benzaldehyde at -78'C gives predominately the threo aldol diastereomer.

Catalytic asymmetric Darzens condensatio
โœ Shigeru Arai; Takayuki Shioiri ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 214 KB

The catalytic asymmetric Darzens condensation promoted by the quaternary ammonium salt (PTC A) derived from cinchonine as a phase-transfer catalyst is described. Treatment of phenacyl chloride with various aldehydes under mild reaction conditions afforded the corresponding desired product in good yi