𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Aldol condensations of chiral α-haloimidates. A chiral darzens condensation procedure.

✍ Scribed by Ahmed Abdel-Magid; Ivan Lantos; Lendon N. Pridgen

Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
214 KB
Volume
25
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

Sumunary: --_-Enantiomerically pure benzyl cis-a,B-epoxycarboxylates were prepared by a modified Darsens procedure utilizing aldx condensation reactions of chiral a-haloimidates with various aldehydes.

A unique chirality reversal was observed using Zincenolates.

📜 SIMILAR VOLUMES

Aldol condensations of chiral ethylketon
Aldol condensations of chiral ethylketones: Control by chiral boron reagents.
✍ Ian Paterson; M. Anne Lister 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 302 KB

The chiral reagents (+)-and (-)-Ipc)2BOTf, in the presence of Et3N, are used to control the aldol condensation reactions of chiral ethylketone 5 with prochiral aldehydes. The SS isomer, 6 or 8, or SA isomer, 7 or 9, is then formed in >99% ee and with up to 93% diastereoselectivity. The use of chira

Studies in macrolide synthesis: aldol co
Studies in macrolide synthesis: aldol condensations of chiral ethylketones via boron enolates.
✍ Ian Paterson; Cynthia K McClure 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 341 KB

A/do/ condensation of chiraal ethylketones 8 and 9,via their 9-BBN or "BupB eno/ates,with methacrolein and acetaldehyde gives mainly the &&&I adduct, 8 -+ 14 or 9 + 18. The chiral reagent (+)-(lpc)~OTf, in the presence of EL& is used to enhance the formation of 14 and 78, while