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Diastereoisomeric ent-Labdane Diterpenoids from Andrographis paniculata

✍ Scribed by Yong-Mei Hu; Guo-Cai Wang; Ying Wang; Herman H.-Y. Sung; Ian D. Williams; Wen-Cai Ye

Publisher: John Wiley and Sons
Year: 2012
Tongue: German
Weight: 374 KB
Volume: 95
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.201100236

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✦ Synopsis

Four C(8),C(12)-diastereoisomers, (8S,12S)-isoandrographolide (1), (8S,12R)-isoandrographolide (2), (8R,12R)-isoandrographolide (3), and (8R,12S)-isoandrographolide (4) were isolated from the aerial parts of Andrographis paniculata. The structures of the new compounds 1 -3 were established on the basis of the spectroscopic data including UV, IR, NMR, HR-ESI-MS, and X-ray diffraction analysis.

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