Diastereo- and Enantioselective Synthesi
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Philippe Bisel; Elke Breitling; August Wilhelm Frahm
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Article
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1998
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John Wiley and Sons
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English
โ 410 KB
๐ 1 views
The hitherto unknown (+)-and (ฯช)-cis-2-aminocyclobutanols 6a,b and 7a,b, as well as the corresponding benzyloxycyclobutanamines 8a,b, have been synthesized by means of asymmetric reductive amination, with de values of 100% and ee values ranging from 96.9 to 99.8%. The relative cis configu-Second-gen