✦ LIBER ✦

Diagnosis of carbohydrate-deficient glycoprotein syndrome by matrix-assisted laser desorption time-of-flight mass spectrometry

✍ Scribed by Yoshinao Wada; Jianguo Gu; Nobuhiko Okamoto; Koji Inui

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 156 KB
Volume: 23
Category: Article
ISSN: 1076-5174
DOI: 10.1002/bms.1200230211

No coin nor oath required. For personal study only.

✦ Synopsis

Serum transferrin from patients with carbohydrate-deficient glycoprotein syndrome was analysed by matrixassisted laser desorption time-of-flight mass spectrometry (MALDI-TOF mass spectrometry). Abnormal molecular species with a defect of one or two oligosaccharide chains of 2200 Da were clearly identified. MALDI-TOF mass spectrometry will serve to diagnose this aetiologically unknown, metabolic disease.

📜 SIMILAR VOLUMES

Characterization of Aspergillus spores b

Characterization of Aspergillus spores by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

✍ Tzu-Ying Li; Biing-Hui Liu; Yu-Chie Chen 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB 👁 2 views

Quantitative analysis of antibiotics by

Quantitative analysis of antibiotics by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

✍ Yong-Chien Ling; Lihnian Lin; Yi-Ting Chen 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 2 views

Comparative studies of the matrix-assisted laser desorption/ionization (MALDI) of 30 antibiotics were made using a-cyano-4-hydroxycinnamic acid (HCCA), 2,5-dihydroxybenzoic acid (DHB), 5,10,15,20tetrakis(4-hydroxyphenyl)-21H,23H-porphyrin and meso-tetra(N-methyl-4-pyridyl)porphyrin matrices. Most an

Structural Analysis of Cartilage Proteog

Structural Analysis of Cartilage Proteoglycans and Glycoproteins Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

✍ Joseph Zaia; Beishan Liu; Raymond Boynton; Frank Barry 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 114 KB

Cartilage extracellular matrix molecules synthesized and maintained by chondrocytes form a strong, elastic tissue functioning to cushion and protect the subchondral bone. Osteoarthritis is characterized by degradation of cartilage extracellular matrix molecules resulting in fibrillation, irreversibl

Oligonucleotide Sequencing by Fragmentat

Oligonucleotide Sequencing by Fragmentation in Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry

✍ Y.F. Zhu; N.I. Taranenko; S.L. Allman; N.V. Taranenko; S.A. Martin; L.A. Haff; C 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 214 KB 👁 3 views

Oligonucleotide sequencing by fragmentation in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry has been demonstrated. With this sequencing method, the preparation of oligonucleotide ladder products and gel electrophoresis are not required, thus the sequencing

Identification of bacteria using matrix-

Identification of bacteria using matrix-assisted laser desorption ionization time-of-flight mass spectrometry

✍ Mollie G. Kedney; Kevin B. Strunk; Lisa M. Giaquinto; Jennifer A. Wagner; Sidney 📂 Article 📅 2007 🏛 The American Society for Biochemistry and Molecula 🌐 English ⚖ 378 KB 👁 2 views

Enhanced mass resolution in matrix-assis

Enhanced mass resolution in matrix-assisted laser desorption/ionization linear time-of-flight mass spectrometry

✍ S. Schuerch; M. Schaer; K. O. Boernsen; U. P. Schlunegger 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 465 KB 👁 2 views

The limits of performance of a linear time-of-flight mass spectrometer using matrix-assisted laser desorp tionlionization have been tested. Effects of the pressure in the vacuum system and the sampling rate of the digital oscilloscopes on mass resolution have been investigated. Spectra recorded at d