✦ LIBER ✦

Developmental toxicity of the HIV-protease inhibitor indinavir in rats

✍ Scribed by Riecke, Kai ;Schulz, Thomas G. ;Shakibaei, Mehdi ;Krause, Bernd ;Chahoud, Ibrahim ;Stahlmann, Ralf

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 570 KB
Volume: 62
Category: Article
ISSN: 0040-3709
DOI: 10.1002/1096-9926(200011)62:5<291::aid-tera3>3.0.co;2-a

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Asymmetric hydrogenation of tetrahydropy

Asymmetric hydrogenation of tetrahydropyrazines: Synthesis of (S)-piperazine-2-tert-butylcarboxamide, an intermediate in the preparation of the HIV protease inhibitor indinavir

✍ K. Rossen; Steven A. Weissman; J. Sager; R.A. Reamer; D. Askin; R.P. Volante; P. 📂 Article 📅 1995 🏛 Elsevier Science 🌐 French ⚖ 242 KB

A pharmacokinetic evaluation of HIV prot

A pharmacokinetic evaluation of HIV protease inhibitors, cyclic ureas, in rats and dogs

✍ Y. Nancy Wong; Deborah L. Burcham; Philip L. Saxton; Susan Erickson-Viitanen; Ma 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 425 KB 👁 2 views

## Abstract The pharmacokinetics of a series of novel cyclic, non‐peptide inhibitors of HIV protease were studied in rats or dogs after intravenous and oral administration. Six symmetrically substituted cyclic urea compounds (XK234, XM311, XM320, XM321, XM323, and XM412), which effectively inhibite

Further evaluation of the developmental

Further evaluation of the developmental toxicity of tributyltin chloride in rats

✍ Makoto Ema; Reiko Kurosaka; Hiro Amano; Yoshiyuki Ogawa 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 641 KB

Developmental Toxicity of JP-8 Jet Fuel

Developmental Toxicity of JP-8 Jet Fuel in the Rat

✍ James R. Cooper; David R. Mattie 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB 👁 1 views

JP-8 aviation fuel is being phased in as a replacement for both JP-4 and JP-5 jet fuels presently in use by the Air Force and Navy, respectively. At the present time, 11% of active-duty Air Force personnel are women of child-bearing age. This study was undertaken to determine the threat posed to the

Developmental toxicity studies of caprol

Developmental toxicity studies of caprolactam in the rat and rabbit

✍ Dr. Shayne C. Gad; Keith Robinson; David G. Serota; Barbara R. Colpean 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 888 KB

Caprolactam was evaluated for developmental toxicity potential in both rats and rabbits by the oral route. In rats dosed on days 6-15 of gestation with 100,500 or 1000 mg/kg/day of caprolactam, the maternal survival rate was significantly lower in the high-dose group and implantation efficiencies we

Developmental toxicity of the topoisomer

Developmental toxicity of the topoisomerase inhibitor, etoposide, in rabbits after intravenous administration

✍ Tetsuji Nagao; Shinsuke Yoshimura; Yoshiaki Saito; Kiyoshi Imai 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 2 views

The developmental effect of the topoisomerase inhibitor, etoposide, was investigated in pregnant rabbits given intravenous doses during early organogenesis. Does received 0, 0.25, 0.5, 1, or 2 mg/kg/day on days 7 through 9 of gestation. Fetal parameters were evaluated on day 28 of gestation. Live fe