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Development of the diurnal rhythm of chick 3-hydroxy-3-methylglutaryl-CoA reductase

โœ Scribed by H. Ramirez; M. J. Alejandre; E. Garcia-Peregrin


Book ID
112773378
Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
227 KB
Volume
17
Category
Article
ISSN
0024-4201

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Addition of hemoglobin, methemoglobin, hemin or hematin in the assay mixture of rat liver 3-hydroxy-3-methylglutaryl CoA (HMGCoA) reductase inhibited the activity of the enzyme. The inhibition by hemin was rapid, without any apparent dependence on time of preincubation. At 20 microM hemin, a maximum