Metabotropic glutamate receptors have been implicated in plasticity in the hippocampus and cerebellum. Are they also involved in plasticity in the visual cortex? This is a complicated question because of the diversity of metabotropic glutamate receptors and the variations in both receptors and plast
Development of orientation preference in the mammalian visual cortex
✍ Scribed by Chapman, Barbara ;G�decke, Imke ;Bonhoeffer, Tobias
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 131 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-3034
No coin nor oath required. For personal study only.
✦ Synopsis
Recent experiments have studied the development of orientation selectivity in normal animals, visually deprived animals, and animals where patterns of neuronal activity have been altered. Results of these experiments indicate that orientation tuning appears very early in development, and that normal patterns of activity are necessary for its normal development. Visual experience is not needed for early devel-opment of orientation, but is crucial for maintaining orientation selectivity. Neuronal activity and vision thus seem to play similar roles in the development of orientation selectivity as they do in the development of eyespecific segregation in the visual system.
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