The role played by environmental influences in the development of the nervous system has been subject to intense study for the last three decades. Many laboratories are currently engaged in characterizing the exact contributions of activity-dependent or -independent processes to the development of t
Early explorations of the development and plasticity of the visual cortex: A personal view
β Scribed by Wiesel, Torsten N.
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 23 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-3034
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Recent experiments have studied the development of orientation selectivity in normal animals, visually deprived animals, and animals where patterns of neuronal activity have been altered. Results of these experiments indicate that orientation tuning appears very early in development, and that normal
Visually driven activity is not required for the establishment of ocular dominance columns, orientation columns, and long-range horizontal connections in visual cortex, although spontaneous activity appears to be necessary. The role of activity may be instructive or simply permissive; evidence for a
We used quantitative autoradiography to determine whether the development of glutamate receptors correlates with the plastic period for monocular deprivation in rat visual cortex. To study glutamate receptors, we incubated sections of rat visual cortex with tritiated (1)-5-methyl-10,11-dihydro-5H-di