Development of Novel Vaccines: Skills, Knowledge and Translational Technologies

✍ Scribed by Şefik Ş. Alkan (auth.), Alexander von Gabain, Christoph Klade (eds.)

Publisher: Springer-Verlag Wien
Year: 2012
Tongue: English
Leaves: 318
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.

✦ Table of Contents

Front Matter....Pages i-xiii
Skills, Knowledge, and Translational Technologies Leading to Novel Vaccines....Pages 1-26
Finding Protective Bacterial Antigens....Pages 27-44
Enhancing and Tailoring the Immunogenicity of Vaccines with Novel Adjuvants....Pages 45-72
Vaccine Delivery: Beyond Needles....Pages 73-86
Employing Live Microbes for Vaccine Delivery....Pages 87-124
Synthesizing Vaccines with Microbes....Pages 125-144
Purification and Formulation: Silent but Important Players in Vaccine Development....Pages 145-188
Cutting-Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines....Pages 189-204
Cutting Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines....Pages 205-232
Examples of Novel Registered Prophylactic Vaccines, HPV, and JEV....Pages 233-286
The Bumpy Road Toward Vaccine Registration: How to Overcome Regulatory Hurdles....Pages 287-300
Back Matter....Pages 301-303

✦ Subjects

Vaccine; Pharmaceutical Sciences/Technology; Immunology; Laboratory Medicine

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