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Development of excitability in embryonic chick skeletal muscle cells

✍ Scribed by Masaakira Kano

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
541 KB
Volume
86
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

During embryonic and early postnatal development, the chick leg muscle cells undergo a series of changes in their electrical responses in the following sequence: passive response, plateau response, plateau plus spike response and spike response. This suggests that the electrogenetic mechanism of muscles matures during development; a mechanism producing the plateau may first be induced, and then that producing the spike. The plateau is sensitive to manganese or cobalt ions, while the spike to tetrodotoxin. This suggests that the plateau is related to the increase in permeability to calcium ions, while the spike to sodium ions.

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