๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Development of a general method of limited sampling for the determination of AUC for a drug that displays two-compartment pharmacokinetics

โœ Scribed by S. B. Duffull; E. J. Begg; J. J. Deely

Book ID
105922995
Publisher
Springer
Year
1999
Tongue
English
Weight
113 KB
Volume
55
Category
Article
ISSN
0031-6970

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Oral and IV dosing: A method to determin
Oral and IV dosing: A method to determine the compartment of drug elimination for two-compartment models
โœ J.W.T. Yates; P.A. Arundel ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 91 KB

It has been shown previously that it is impossible to measure the volume of distribution at steady state conclusively for a multicompartment system from an iv bolus dose only. The problem lies in deciding from which compartment elimination of the drug occurs in the compartmental model. In this paper

A LIMITED SAMPLING METHOD FOR THE ESTIMA
A LIMITED SAMPLING METHOD FOR THE ESTIMATION OF FLUNARIZINE AREA UNDER THE CURVE (AUC) AND MAXIMUM PLASMA CONCENTRATION (CMAX)
โœ IFTEKHAR MAHMOOD; J. TODD SAHLROOT ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 553 KB

A limited sampling model has been developed for ยฏunarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (C max ). The model was developed using training data sets f

Development of a chromatographic method
Development of a chromatographic method for the determination of saquinavir in plasma samples of HIV patients
โœ M. A. Campanero; M. Escolar; M. A. Arangoa; B. Sรกdaba; J. R. Azanza ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 85 KB ๐Ÿ‘ 2 views

## Abstract A simple, sensitive and reproducible highโ€performance liquid chromatographic method for detecting and quantifying saquinavir in human plasma is described. Verapamil was used as internal standard. The method employes a single liquidโ€“liquid extraction step with __tert__โ€butil methyl ether