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Development and validation of a rapid HPLC method for the determination of ascorbic acid, phenylephrine, paracetamol and caffeine using a monolithic column

✍ Scribed by Koblová, Petra; Sklenářová, Hana; Brabcová, Ivana; Solich, Petr

Book ID
111654835
Publisher
The Royal Society of Chemistry
Year
2012
Tongue
English
Weight
171 KB
Volume
4
Category
Article
ISSN
1759-9660

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## Abstract A new rapid, sensitive and validated HPLC method has been developed for the determination of methylxanthines and their metabolites in asthmatic patients. The method was initiated by using spiked urine samples on a silica monolithic column as a novel packing material. The mobile phase co