Development and validation of a rapid an
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Noha N. Atia; Peter York; Brian J. Clark
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Article
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2009
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John Wiley and Sons
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English
⚖ 542 KB
## Abstract A new rapid, sensitive and validated HPLC method has been developed for the determination of methylxanthines and their metabolites in asthmatic patients. The method was initiated by using spiked urine samples on a silica monolithic column as a novel packing material. The mobile phase co