Development and validation of a LC/MS/MS method for simultaneous quantification of oxcarbazepine and its main metabolites in human serum
✍ Scribed by G. Paglia; O. D’Apolito; D. Garofalo; C. Scarano; G. Corso
- Book ID
- 108159792
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 331 KB
- Volume
- 860
- Category
- Article
- ISSN
- 1873-376X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
An analytical method based on liquid–liquid extraction has been developed and validated for analysis of agomelatine in human plasma. Fluoxetine was used as an internal standard for agomelatine. A Betasil C18 (4.0 × 100 mm, 5 µm) column provided chromatographic separation of analytes followed by dete
A sensitive LC-MS-MS method capable of quantifying terfenadine at levels down to 100 pg ml-1 in human plasma is reported. The method was validated over a linear range from 0.1 to 5.0 ng ml-1 using a liquid-liquid extraction with a deuterium-labelled internal standard. The between-run precision and a