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Development and validation of a LC-MS/MS assay for quantitation of plasma citrulline for application to animal models of the acute radiation syndrome across multiple species

✍ Scribed by Jones, Jace W.; Tudor, Gregory; Bennett, Alexander; Farese, Ann M.; Moroni, Maria; Booth, Catherine; MacVittie, Thomas J.; Kane, Maureen A.


Book ID
125342029
Publisher
Springer
Year
2014
Tongue
English
Weight
728 KB
Volume
406
Category
Article
ISSN
1618-2650

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## ABSTRACT A highly sensitive, specific and simple LC‐MS/MS method was developed for the simultaneous estimation of dexlansoprazole (DEX) with 50 μL of human plasma using omeprazole as an internal standard (IS). The API‐4000 LC‐MS/MS was operated under multiple reaction‐monitoring mode using elect