## Abstract Recently, promising fasciocidal activities of artesunate and artemether were described in rats and sheep. Therefore, a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed to quantify artesunate, artemether and their metabolites dihydroartemisinin and dihydroar
✦ LIBER ✦
Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active metabolite dihydroartemisinin in human plasma
✍ Scribed by Liusheng Huang; Anura L. Jayewardene; Xiaohua Li; Florence Marzan; Patricia S. Lizak; Francesca T. Aweeka
- Book ID
- 108189683
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 338 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0731-7085
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## Abstract Cyadox is a novel antimicrobial growth‐promoter of the quinoxalines. For food safety and pharmacokinetic studies, a convenient, sensitive and reproducible LC‐ESI‐MS/MS method was developed for the simultaneous determination of cyadox and its major metabolites, quinoxaline‐2‐carboxylic a