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Selective determination, in plasma, of artemether and its major metabolite, dihydroartemisinin, by high-performance liquid chromatography with ultraviolet detection

โœ Scribed by C.G. Thomas; S.A. Ward; G. Edwards


Publisher
Elsevier Science
Year
1992
Weight
301 KB
Volume
583
Category
Article
ISSN
0378-4347

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A method for the determination of bupropion and its three major basic metabolites in plasma is described. Following an extraction from alkaline plasma into 1.5% v/v isoamyl alcohol in n-heptane, a portion of the acid-backwashed extract was injected onto a column packed with trimethylsilyl reverse-ph