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Deuterium labeled procyanidin syntheses

✍ Scribed by Marie-Clotilde Pierre; Catherine Chèze; Joseph Vercauteren

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
263 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

Deuterium-labeled procyanidins have been prepered by hemisynthesis from taxifolin in order to investigate their metabolism in human. The structures of the desired deuterated natural compounds B3 10D (RI=D, R2=H) and B4 13D (RI=D, R2=-H) were proven by spectroscopic and physical properties means, including 2H NMR spectrum. By-products with unatural absolute configuration at some centers were also formed along the process and were characterised.

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