Determining the longitudinal relaxation time (T1) of blood at 3.0 Tesla

✍ Scribed by Hanzhang Lu; Chekesha Clingman; Xavier Golay; Peter C.M. van Zijl

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 110 KB
• Volume: 52
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.20178

✦ Synopsis

Abstract

It is important to determine the longitudinal relaxation time of blood for black blood imaging, as well as for quantifying blood flow by arterial spin labeling (ASL). In this study a circulation system was used to measure blood T~1~ under physiological conditions at the new clinical field strength of 3.0T. It was found that 1/T~1~ in s^−1^ was linearly dependent (P < 0.05) on hematocrit (Hct) within a normal range of 0.38–0.46. The relationships were 1/T~1~ = (0.52 ± 0.15) · Hct + (0.38 ± 0.06) and 1/T~1~ = (0.83 ± 0.07) · Hct + (0.28 ± 0.03) for arterial (oxygenation = 92% ± 7%) and venous blood (69% ± 8%), respectively, which led to estimated T~1~ values of 1664 ± 14 ms (arterial) and 1584 ± 5 ms (venous) at a typical human Hct of 0.42. The temperature dependencies of blood T~1~ were 22.3 ± 0.6 ms/°C and 19.8 ± 0.8 ms/°C for Hct values of 0.42 and 0.38, respectively. When a head coil transmit/receive setup was used, radiation damping caused a slight reduction (19 ms) of the measured T~1~ values. Magn Reson Med 52:679–682, 2004. © 2004 Wiley‐Liss, Inc.