𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparison of longitudinal metabolite relaxation times in different regions of the human brain at 1.5 and 3 Tesla

✍ Scribed by Thomas Ethofer; Irina Mader; Uwe Seeger; Gunther Helms; Michael Erb; Wolfgang Grodd; Albert Ludolph; Uwe Klose

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
154 KB
Volume
50
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

In vivo longitudinal relaxation times of N‐acetyl compounds (NA), choline‐containing substances (Cho), creatine (Cr), myo‐inositol (mI), and tissue water were measured at 1.5 and 3 T using a point‐resolved spectroscopy (PRESS) sequence with short echo time (TE). T~1~ values were determined in six different brain regions: the occipital gray matter (GM), occipital white matter (WM), motor cortex, frontoparietal WM, thalamus, and cerebellum. The T~1~ relaxation times of water protons were 26–38% longer at 3 T than at 1.5 T. Significantly longer metabolite T~1~ values at 3 T (11–36%) were found for NA, Cho, and Cr in the motor cortex, frontoparietal WM, and thalamus. The amounts of GM, WM, and cerebrospinal fluid (CSF) within the voxel were determined by segmentation of a 3D image data set. No influence of tissue composition on metabolite T~1~ values was found, while the longitudinal relaxation times of water protons were strongly correlated with the relative GM content. Magn Reson Med 50:1296–1301, 2003. © 2003 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

1H metabolite relaxation times at 3.0 te
1H metabolite relaxation times at 3.0 tesla: Measurements of T1 and T2 values in normal brain and determination of regional differences in transverse relaxation
✍ Frank Träber; Wolfgang Block; Rolf Lamerichs; Jürgen Gieseke; Hans H. Schild 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 258 KB

## Abstract ## Purpose To measure ^1^H relaxation times of cerebral metabolites at 3 T and to investigate regional variations within the brain. ## Materials and Methods Investigations were performed on a 3.0‐T clinical whole‐body magnetic resonance (MR) system. T2 relaxation times of N‐acetyl as

Comparison of T1 relaxation times of the
Comparison of T1 relaxation times of the neurochemical profile in rat brain at 9.4 tesla and 14.1 tesla
✍ Cristina Cudalbu; Vladimír Mlynárik; Lijing Xin; Rolf Gruetter 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 430 KB

## Abstract Knowledge of __T__~1~ relaxation times can be important for accurate relative and absolute quantification of brain metabolites, for sensitivity optimizations, for characterizing molecular dynamics, and for studying changes induced by various pathological conditions. ^1^H __T__~1~ relaxa

NOE Enhancements and T1 Relaxation Times
NOE Enhancements and T1 Relaxation Times of Phosphorylated Metabolites in Human Calf Muscle at 1.5 Tesla
✍ Truman R. Brown; Radka Stoyanova; Tamela Greenberg; Ravi Srinivasan; Joseph Murp 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 474 KB 👁 1 views

## Abstract Nuclear Overhauser effect (NOE) enhancements and relaxation times of ^31^P metabolites in human calf were measured in 12 volunteers (4 men and 8 women) at 1.5 T using a dual tuned four‐ring birdcage. The NOE enhancements of inorganic phosphate (__P__~1~), phosphocreatine (PCr), γ‐, α‐,

Proton T1 relaxation times of cerebral m
Proton T1 relaxation times of cerebral metabolites differ within and between regions of normal human brain
✍ E. E. Brief; K. P. Whittall; D. K. B. Li; A. MacKay 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB

## Abstract Saturation recovery spectra (STEAM) were acquired at 1.5 T with 7 __TR__s ranging from 530 to 5000 ms and a constant __TE__ of 30 ms in voxels (7.2 ml) located in occipital grey, parietal white and frontal white matter (10 subjects each location). Spectra were also acquired at 7, 21 and