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NOE Enhancements and T1 Relaxation Times of Phosphorylated Metabolites in Human Calf Muscle at 1.5 Tesla

✍ Scribed by Truman R. Brown; Radka Stoyanova; Tamela Greenberg; Ravi Srinivasan; Joseph Murphy-Boesch

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
474 KB
Volume
33
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Nuclear Overhauser effect (NOE) enhancements and relaxation times of ^31^P metabolites in human calf were measured in 12 volunteers (4 men and 8 women) at 1.5 T using a dual tuned four‐ring birdcage. The NOE enhancements of inorganic phosphate (P~1~), phosphocreatine (PCr), γ‐, α‐, and β‐nucleoside triphosphate (NTP) from 19 measurements were 0.51 ± 0.10, 0.64 ± 0.03, 0.53 ± 0.03, 0.56 ± 0.08, and 0.47 ± 0.05, respectively. The relaxation times were independent of proton irradiation and from 23 measurements were 3.49 ± 0.35, 4.97 ± 0.58, 4.07 ± 0.36, 2.90 ± 0.25, and 3.61 ± 0.25 s for P~1~, PCr, γ‐, α‐, and β‐NTP, respectively. No significant differences between gender and age were observed for either NOE enhancements or relaxation times. Also, among nine volunteers, we observed no significant differences in T~1~ between the coupled and decoupled cases.

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