## Abstract The synthesis of hydrazone derivatives containing thiazole unit was achieved with condensation of thiosemicarbazones and ω‐bromoacetophenone at room temperature. This mild, convenient, and efficient method affords the desired products with good to excellent yields. Their structures have
Determination of thiosemicarbazones by reaction with ω-bromoacetophenone
✍ Scribed by Jyoti Talegaonkar; Suman Mukhija; K.S. Boparai
- Book ID
- 118993701
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 126 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0039-9140
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📜 SIMILAR VOLUMES
## Abstract Phenacyl bromide 1 reacts with ethyl cyanoacetate 2 in presence of piperidine catalyst to afford the hexa‐2,4‐diene derivative 5. Ethyl phenacylcyanoacetate 3 was obtained by reaction of 1 with the sodium salt 6. Compound 3 reacts with hydrazines and trichloroacetonitrile to afford the
o-Bromoacetophenone reacts with the sodium salt of ethyl cyanoacetate to afford a-cyano-P-phenyl-A".Pbutenolide. This butenolide undergoes azo coupling with diazotized aromatic amines (ArNHJ to afford the hydrazo derivatives. These hydrazo derivatives (Ar= Ph, were transformed into the corresponding