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Determination of the absolute configuration of cycloheximide

✍ Scribed by Howard J. Schaeffer; Vijay K. Jain


Publisher
John Wiley and Sons
Year
1961
Tongue
English
Weight
72 KB
Volume
50
Category
Article
ISSN
0022-3549

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Determination of the Absolute Configurat
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## Resolution of pentahelicene (4) was recently described['! We have now succeeded in the first allocation of absolute configuration to a helicene, namely to (+ )-( 4). The fundamental investigations of Mislow et al. ['], later confirmed by X-ray structure analysis[31, have shown that

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In the past, Chirality has published a few review articles focused on some methods useful for determination of absolute configuration. However, in view of the rapid progress in the field, and in particular, of the recent advancement of computational methods, we found it appropriate to summarize the