Determination of the Absolute Configuration of Chiral 1,3-Diols by CD spectroscopy of their [Mo2(OAc)4] complexes
β Scribed by Dr. Jadwiga Frelek; Wojciech Szczepek; Wolfgang Voelter
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 449 KB
- Volume
- 339
- Category
- Article
- ISSN
- 1615-4150
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π SIMILAR VOLUMES
The in situ complexes of dimolybdenum tetraacetate [Mo 2 (OAc) 4 ] with vicinal diols give CD spectra suitable for determination of their absolute configuration. Positive (negative) torsional angle in the O-C-C-O moiety leads to a positive (negative) Cotton effect at around 300 nm. The extension of
Each of the chiral 1,2-and 1,3-diols examined was derivatized exclusively to a single diastereomeric acetal by the use of a new axially chiral reagent, 2%-methoxy-1,1%-binaphthalene-8-carbaldehyde (MBC). The absolute configuration of the original 1,2-and 1,3-diols was determined by the NOE correlati
In connection with the structure elucidation of cherylline (l), we have determined the