๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Determination of stereochemistry and separation of diastereomeric derivatives of trans-2-pyridylcyclohexanols by extraction

โœ Scribed by Masato Matsugi; Masatomo Nojima; Yuri Hagimoto; Yasuyuki Kita

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
92 KB
Volume
42
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

The example of the determination of the stereochemistry and separation of diastereomeric derivatives of trans-2pyridylcyclohexanols by extraction is shown here. The facile separation of the corresponding diastereomers is based on a difference in the basicity of the diastereomers.

๐Ÿ“œ SIMILAR VOLUMES

Determination of absolute configuration
Determination of absolute configuration of trans-2-arylcyclohexanols using remarkable aryl-induced 1H NMR shifts in diastereomeric derivatives
โœ Masato Matsugi; Kinuyo Itoh; Masatomo Nojima; Yuri Hagimoto; Yasuyuki Kita ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 110 KB

A facile determination of the absolute configuration of trans-2-arylcyclohexanols was achieved. It takes advantage of the observations of the remarkable aryl-induced 1 H NMR shifts that seems to be ascribable to the discrimination of the diastereo-environment between intermediary optically active di

Determination of Absolute Stereochemistr
Determination of Absolute Stereochemistry of 2-Alkylmorpholines by a 13C NMR Study of Steroid Derivatives
โœ L. Fielding; N. Hamilton; R. McGuire; M. Maidment; A. C. Campbell ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 340 KB ๐Ÿ‘ 2 views

Information about the absolute stereochemistry (configuration) of some diastereomeric pairs of 28-(2alkylmorpholinyl)-3a-hydroxy-5a-pregnanes is available from the 13C chemical shifts of the C-3' and C-5' morpholine carbons. A series of anaesthetic compounds can be allocated to one group of R config

Stereochemistry of nucleophilic attack i
Stereochemistry of nucleophilic attack in the solvolyses of cis- and trans-2-methylcyclobutylcarbinyl derivatives
โœ Joseph J. Gajewski; Ronald L. Lyle; Robert P. Gajewski ๐Ÿ“‚ Article ๐Ÿ“… 1970 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 223 KB

Despite the fact that cyclobutylcarbinyl arenesulfonates solvolyze 102-lo3 times faster than appropriate models indicating carbon participation in the ionization, ' the nature of the product-forming intermediate has yet to be investigated in the parent system. We wish to report on the stereochemistr