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Determination of retinol and retinyl esters in human plasma by high-performance liquid chromatography with automated column switching and ultraviolet detection

✍ Scribed by S Hartmann; O Froescheis; F Ringenbach; R Wyss; F Bucheli; S Bischof; J Bausch; U.-W Wiegand

Book ID: 108447677
Publisher: Elsevier Science
Year: 2001
Weight: 541 KB
Volume: 751
Category: Article
ISSN: 0378-4347
DOI: 10.1016/s0378-4347(00)00481-3

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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The clean‐up and separation of the samp