Determination of propranolol enantiomers in human plasma and urine and in rat tissues using chiral stationary-phase liquid chromatography
✍ Scribed by Harumi Takahashi; Satoshi Kanno; Hiroyasu Ogata; Kazuko Kashiwada; Mineko Ohira; Kazuhiko Someya
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 344 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A sensitive, specific and rapid liquid chromatography–mass spectrometry (LC‐MS/MS) method has been developed and validated for enantioselective determination of darusentan enantiomers, orally active potent endothelin‐A receptor antagonist, in rat plasma. The plasma samples were pretreat
## Abstract A simple, rapid, and efficient method, dispersive liquid–liquid microextraction (DLLME) coupled with high‐performance liquid chromatography‐fluorescence detector, has been developed for the determination of guaifenesin (GUA) enantiomers in human urine samples after an oral dose administ
We report a method for the high-performance liquid chromatographic (HPLC) chiral separation of racemic clenbuterol in human plasma. Human plasma was spiked with stock solutions of clenbuterol hydrochloride and practolol as the internal standard. Following a liquid-liquid extraction procedure with 10