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Determination of pentopril, an angiotensin converting enzyme inhibitor, and its active metabolite in urine

✍ Scribed by V. Tipnis; A. Rakhit


Publisher
Elsevier Science
Year
1985
Weight
393 KB
Volume
345
Category
Article
ISSN
0378-4347

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The disposition characteristics of pentopril (the ethyl ester) and its active carboxylic acid metabolite (CGS 13934) were determined in conscious rats after separate intravenous administrations of both compounds. The relationship between plasma concentration and pharmacological effect was also evalu