Determination of griseofulvin in skin, plasma, and sweat

✍ Scribed by Vinod P. Shah; S. Riegelman; William L. Epstein

• Publisher: John Wiley and Sons
• Year: 1972
• Tongue: English
• Weight: 300 KB
• Volume: 61
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600610434

✦ Synopsis

A procedure is described for the quantitative determination of griseofulvin in skin, plasma, and sweat. Griseofulvin is extracted with ether from skin and is measured quantitatively by GLC and an electron-capture detector, using diazepam as an internal standard. Griseofulvin from plasma and sweat is extracted with ether and measured spectrophotofluorometrically.

Keyphrases 0 Griseofulvin-GLC determination in skin, spectrophotofluorometric determination in plasma and sweat 0 GLCdetermination of griseofulvin in skin Spectrophotofluorometrydetermination of griseofulvin in plasma and sweat