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Determination of free and total warfarin concentrations in plasma using UPLC MS/MS and its application to a patient samples

โœ Scribed by Mahasen A. Radwan; Ghada A. Bawazeer; Nouf M. Aloudah; Bushra T. AlQuadeib; Hassan Y. Aboul-Enein

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
215 KB
Volume
26
Category
Article
ISSN
0269-3879

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## Abstract A sensitive and selective LCโ€MS/MS method was developed and validated for the determination of aconitine in microdialysate and rat plasma. Extraction of plasma sample was conducted by use of 1% trichloracetic acid and acetonitrile solution with 10 ng/mL internal standard (propafenone) s