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Determination of Cyclodextrin-Guest Association Constants by Competition with Indicator Dyes

✍ Scribed by Hirsch, Warren; Choy, Cheuk Kwong; Ng, Kok Wing; Fried, Vojtech


Book ID
120400617
Publisher
Taylor and Francis Group
Year
1989
Tongue
English
Weight
252 KB
Volume
22
Category
Article
ISSN
0003-2719

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Drug–Cyclodextrin Association Constants
✍ Angelina Angelova; Catherine Ringard-Lefebvre; Adam Baszkin πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 76 KB

The complexation reaction between the amphiphilic peptide antibiotic polymyxin B and naturally occurring cyclodextrins, used as potential drug carriers, was quantitatively evaluated from surface tension measurements at various drug concentrations. The association constant, Ka, of polymyxin B:beta-cy