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Determination of Conformer-Specific Partition Coefficients in Octanol/Water Systems

✍ Scribed by Kraszni, Márta; Bányai, István; Noszál, Béla

Book ID
119960384
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
137 KB
Volume
46
Category
Article
ISSN
0022-2623

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Determination of octanol-water partition
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✍ V. Makovskaya; J.R. Dean; W.R. Tomlinson; S.M. Hitchen; M. Comber 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 835 KB

The use of liquid chromatography to estimate octanol-water partition coefficients, log k,,, has been demonstrated. The capacity factor with a mobile phase of 100% water, k,, has been found to be a useful chromatographic parameter. Values of k, were derived from a computer software package (Hipac-G),