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Determination of chromatographic and spectrophotometric dissociation constants of some beta lactam antibiotics

✍ Scribed by Ebru Çubuk Demiralay; Duygu Koç; Y. Doğan Daldal; Cansel Çakır

Book ID
118477685
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
751 KB
Volume
71
Category
Article
ISSN
0731-7085

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Chromatographic determination of aqueous
Chromatographic determination of aqueous dissociation constants of some water-insoluble nonsteroidal antiinflammatory drugs
✍ Oumada, Fadoua Z. (author);Raand̀fols, Clara (author);Roseand́s, Martiand́ (auth 📂 Article 📅 2002 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 140 KB

The purpose of this work is to propose a new, useful, and easy chromatographic method to determine accurately the aqueous dissociation constant of drugs sparingly soluble in water. The method uses the rigorous intersolvental pH scale, (w)(s)pH, i.e., the pH measurements are made in the mobile phase