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Chromatographic Determination of Dissociation Constants of Pramipexole and its Impurities

✍ Scribed by B. Jančić; M. Medenica; D. Ivanović; A. Malenović

Book ID
111790723
Publisher
Springer
Year
2007
Tongue
English
Weight
215 KB
Volume
65
Category
Article
ISSN
0009-5893

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Chromatographic determination of aqueous
Chromatographic determination of aqueous dissociation constants of some water-insoluble nonsteroidal antiinflammatory drugs
✍ Oumada, Fadoua Z. (author);Raand̀fols, Clara (author);Roseand́s, Martiand́ (auth 📂 Article 📅 2002 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 140 KB

The purpose of this work is to propose a new, useful, and easy chromatographic method to determine accurately the aqueous dissociation constant of drugs sparingly soluble in water. The method uses the rigorous intersolvental pH scale, (w)(s)pH, i.e., the pH measurements are made in the mobile phase