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Determination of 3'-deamino-3'-[2(S)-methoxy-4-morpholinyl]doxorubicin, a new morpholinyl anthracycline, in plasma by high-performance liquid chromatography with fluorescence detection

โœ Scribed by M. Breda; E. Pianezzola; M. Strolin Benedetti


Book ID
103804295
Publisher
Elsevier Science
Year
1992
Weight
509 KB
Volume
578
Category
Article
ISSN
0378-4347

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โœ Kazutake Shimada; Makoto Tanaka; Toshio Nambara; Yutaka Imai ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 327 KB

A sensitive method has been developed for the determination of a new antihypertensive agent, (2H,4H)-2-(2-hydroxyphenyl)-3-(3mercaptopropionyl)-4-thiazolidinecarboxylic acid (I), in human blood. Because the drug is unstable in biological fluids, it was immediately derivatized by treating the freshly