Detection of Slit2 promoter hypermethylation in tissue and serum samples from breast cancer patients
β Scribed by Ga-Eon Kim; Kyung Hwa Lee; Yoo Duk Choi; Ji Shin Lee; Jae Hyuk Lee; Jong Hee Nam; Chan Choi; Min Ho Park; Jung Han Yoon
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 314 KB
- Volume
- 459
- Category
- Article
- ISSN
- 1432-2307
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## Abstract We previously proved that p16 promoter methylation present in the tumors of colorectal cancer patients can be detected in the serum of those same patients using methylationβspecific PCR (MSP). To seek the possibility that this technique could be applied to the monitoring of cancer recur
CA-549 is a high molecular weight, circulating marker for breast cancer defined by its reactivity to monoclonal antibody BC4E 549. CA-549 has recently been shown to be elevated in the sera of 50% of advanced breast cancer patients (n = 80), as compared to < 2.0% of benign breast disease patients (n