Raman spectroscopy and multivariate analysis of serum samples from breast cancer patients
✍ Scribed by J. L. Pichardo-Molina; C. Frausto-Reyes; O. Barbosa-García; R. Huerta-Franco; J. L. González-Trujillo; C. A. Ramírez-Alvarado; G. Gutiérrez-Juárez; C. Medina-Gutiérrez
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 243 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0268-8921
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CA-549 is a high molecular weight, circulating marker for breast cancer defined by its reactivity to monoclonal antibody BC4E 549. CA-549 has recently been shown to be elevated in the sera of 50% of advanced breast cancer patients (n = 80), as compared to < 2.0% of benign breast disease patients (n
## Abstract The __BRCA1__ and __BRCA2__ genes are responsible for a high proportion of familial breast cancer; germline mutations in these genes confer a lifetime risk of about 70% for developing breast cancer. Most of the described deleterious mutations are small deletions or insertions that origi