A radioimmunometric sandwich assay for the tumour-associated antigen defined by the monoclonal antibody (MAb) HMFGZ, has been used to measure serum levels of the antigen in 76 healthy controls, 38 ovarian carcinoma patients preoperatively, 98 patients 2 to 6 weeks after surgery and 36 patients at re
Detection of the tumour-associated antigens recognized by the monoclonal antibodies hmfg-1 and 2 in serum from patients with breast cancer
β Scribed by Joy Burchell; Dennis Wang; Joyce Taylor-Papadimitriou
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- French
- Weight
- 589 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0020-7136
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3'I-labelled HMFGl or HMFGl F(ab')2 monoclonal antibody (MAb) was administered intraperitoneally to I S patients with epithelial ovarian cancer who had completed chemotherapy and were in complete or good partial remission. Each patient received 2-3 mCi. Patients were scanned immediately after and un
The cancer-associated epitope defined by the monoclonal antibody (MAb) 9H8 was shown to be closely related to the T antigen (Thornsen-Friedenreich antigen) by its sensitivity to 0-glycanase treatment of a mucin glycopeptide known to express this epitope. The reactivity with this glycopeptide increas