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Detection of recombinant P-glycoprotein in multidrug resistant cultured cells

✍ Scribed by Ursula A. Germann

Book ID
111640092
Publisher
Humana Press Inc
Year
2000
Tongue
English
Weight
159 KB
Volume
14
Category
Article
ISSN
1073-6085

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Regulation of P-glycoprotein (Pgp) expression occurs not only at the DNA and mRNA level but also at the protein level. We showed previously that Pgp was stabilized when multidrug-resistant CH(R)C5 and SKVCR 2.0 ovarian cell lines were subjected to serum-starved or high-cell-density growth conditions