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Effect of liposomes on P-glycoprotein function in multidrug resistant cells

✍ Scribed by Alain R. Thierry; Anatoly Dritschilo; Aquilur Rahman

Book ID
115765312
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
500 KB
Volume
187
Category
Article
ISSN
0006-291X

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Regulation of P-glycoprotein (Pgp) expression occurs not only at the DNA and mRNA level but also at the protein level. We showed previously that Pgp was stabilized when multidrug-resistant CH(R)C5 and SKVCR 2.0 ovarian cell lines were subjected to serum-starved or high-cell-density growth conditions