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Detection of polyoma-virus-induced tumor antigen(S) by macrophage migration inhibition

✍ Scribed by Robert Szigeti; Tina Dalianis; George Klein; Yoshiaki Ito; Göran Magnusson

Publisher
John Wiley and Sons
Year
1982
Tongue
French
Weight
518 KB
Volume
30
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

We have applied the macrophage migration inhibition assay to study cell‐mediated immune responses to antigens of polyoma‐virus‐transformed cells. Macrophages from polyoma‐virus‐immunized mice, but not from control mice, showed significant migration inhibition when exposed to extracts of polyoma‐virus‐induced mouse and rat transformed cells. Extracts of non‐polyoma‐induced tumors had no such effect.

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