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Detection of mismatch repair gene germline mutation carrier among Chinese population with colorectal cancer

✍ Scribed by Hei-Ying Jin; Xiufang Liu; Vicky Ka Ming Li; Yijiang Ding; Bolin Yang; Jianxiang Geng; Rensheng Lai; Shuqing Ding; Min Ni; Ronghua Zhao


Book ID
115011463
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
227 KB
Volume
8
Category
Article
ISSN
1471-2407

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## Abstract Lynch syndrome is defined by the presence of germline mutations in mismatch repair (MMR) genes. Several models have been recently devised that predict mutation carrier status (Myriad Genetics, Wijnen, Barnetson, PREMM and MMRpro models). Families at moderate‐high risk for harboring a Ly