Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with Hereditary non-polyposis colorectal cancer
โ Scribed by SHENG, Jian Qiu ;CHAN, Tsun Leung ;CHAN, Yee Wai ;HUANG, Ji Sheng ;CHEN, Ji Gui ;ZHANG, Ming Zhi ;GUO, Xiu Lan ;MU, Hong ;CHAN, Annie Sy ;LI, Shi Rong ;YUEN, Siu Tsan ;LEUNG, Suet Yi
- Book ID
- 108988692
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 120 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1443-9611
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Hereditary nonpolyposis colorectal cancer (HNPCC) is frequently associated with inherited mutation in one of four DNA mismatch repair genes. Somatic mutations in the same genes are also found in a subset of sporadic colorectal cancers. A defect in DNA mismatch repair results in an RER (replication e
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