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Detection of K-ras mutations in faeces of patients with colorectal tumours, using PCR

✍ Scribed by J.J. Koornstra; A. Ulvik; O. Røkke; J.F. Halvorsen; K. Haug; D. Øgreid


Book ID
116121382
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
95 KB
Volume
48
Category
Article
ISSN
0300-2977

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Detection of K-ras mutations in stools o
✍ Peter Nollau; Carsten Moser; Günter Weinland; Christoph Wagener 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 639 KB

Mutant-enriched PCR was applied to the detection of mutations at codons I 2 and I 3 of K-ras genes in the stools of patients with colorectal cancer. Mutations were analyzed in stool samples obtained prior to surgery. Resected tumor specimens were screened for K-ras mutations by PCR-mediated RFLP ana