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Detection of DNA Fragments Encompassing the Deletion Junction of Mitochondrial Genome

✍ Scribed by Yu-ichi Goto; Ichizo Nishino; Satoshi Horai; Ikuya Nonaka

Book ID
115578451
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
321 KB
Volume
222
Category
Article
ISSN
0006-291X

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While methods for the detection of point mutations and small insertions or deletions in genomic DNA are well established, the detection of larger (>100 bp) genomic duplications or deletions can be more difficult. Most mutation scanning methods use PCR as a first step, but the subsequent analyses are