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Direct DNA sequencing from colony: analysis of multiple deletions of mitochondrial genome

✍ Scribed by Kinji Ohno; Masashi Tanaka; Hidekazu Ino; Hiroshi Suzuki; Michinari Tashiro; Tohru Ibi; Ko Sahashi; Akira Takahashi; Takayuki Ozawa

Book ID
116105959
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
748 KB
Volume
1090
Category
Article
ISSN
0167-4781

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Inclusion body myositis (IBM) is a sporadic progressive myopathy, which is morphologically characterized by inflammatory cell infiltrates and rimmed vacuoles in muscle fibers. Mitochondrial changes are regularly present with ragged-red fibers showing deficiency of cytochrome c oxidase. In these musc