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Detection of the age-dependent 4977 bp deletion of mitochondrial DNA

✍ Scribed by C. Meißner; N. von Wurmb; M. Oehmichen


Publisher
Springer-Verlag
Year
1997
Tongue
German
Weight
79 KB
Volume
110
Category
Article
ISSN
0937-9827

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The abundance of mitochondrial DNA (mtDNA) deletions has been shown to increase with age in a number of species and may contribute to the aging process. Estimating the total mtDNA deletion load of an individual is essential in evaluating the potential physiological impact. In this study, we compared