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Detection of DNA aberrations in human cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products

✍ Scribed by Y. Suzuki; Y. Murakami; M. Orita; K. Hayashi; T. Sekiya


Book ID
113252309
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
89 KB
Volume
253
Category
Article
ISSN
0165-1161

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Analysis of single-stranded conformation polymorphisms in polymerase chain reaction (PCR) products (PCR-SSCP) is a sensitive method for detecting point mutations in genomic DNA. To investigate its utility in examining the androgen receptor gene, we analyzed data on a patient with the testicular femi